Case Files Neuroscience (2nd Edition) by Eugene Toy, Rahul Jandial, Josh Neman, Evan Snyder

By Eugene Toy, Rahul Jandial, Josh Neman, Evan Snyder

Research NEUROSCIENCE within the CONTEXT OF REAL-LIFE sufferers and get ready FOR THE forums

Experience with scientific situations is essential to excelling at the USMLE Step 1 and shelf tests, and eventually to offering sufferers with powerfuble scientific care. Case documents: Neuroscience offers forty nine true-to-life instances that illustrate crucial thoughts during this box. each one case contains an easy-tounderstand dialogue correlated to crucial simple technological know-how ideas, definitions of key words, neuroscience pearls, and USMLE-style evaluation questions.

With Case documents, you'll research rather than memorize.
• research from forty nine high-yield circumstances, each one with board-style questions and key-point pearls
• grasp advanced recommendations via transparent and concise discussions
• perform with evaluate inquiries to strengthen learning
• Polish your method of scientific problem-solving
• excellent for clinical, actual treatment, and neuroscience scholars getting ready for direction tests and the Boards

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What are the pathological findings for this disease? indd 15 7/30/14 7:34 PM 16 CASE FILES: Neuroscience ANSWERS TO CASE 2: The Neuron Summary: A 54-year-old woman with progressive weakness of her arms and legs with subtle speech difficulties is diagnosed with ALS. • Part of nervous system affected: The central nervous system (CNS), specifically the motor neurons. • Fasciculations: ALS is a progressive, neurodegenerative disease affecting motor neurons, which are cells within the CNS that control voluntary muscle movement.

Concentrations of Na+ and Cl− are greater on the outside of the cell, while concentrations of K+ and organic anions, such as charged amino acids and proteins, are greater on the inside of the cell (Table 3-1). The organic ions are incapable of passing across the cell membrane. Because the cell membrane is essentially impermeable to charged particles, ions must rely on specific channels and transporters to gain entry or exit from the neuron. There are two general types of ion channels in the neuron, resting and gated channels.

This provides a low-resistance pathway for the direct flow of electrical potential from one cell to the other. Action potentials that reach the presynaptic terminal directly depolarize the postsynaptic membrane. If the depolarization reaches the threshold for the postsynaptic membrane, an action potential can be generated and propagated through that cell. indd 44 7/30/14 7:33 PM SECTION II: Clinical Cases 45 The transmission of the electrical signal occurs through specialized proteins, which physically connect the two cells.

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